Human THAP3 Recombinant Protein (RPPB4948)
- SKU:
- RPPB4948
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- THAP3
- Synonyms:
- THAP Domain Containing Apoptosis Associated Protein 3
- THAP Domain-Containing Protein 3
- Source:
- Escherichia Coli
- Uniprot:
- Q8WTV1
Frequently bought together:
Description
| Product Name: | Human THAP3 Recombinant Protein |
| Product Code: | RPPB4948 |
| Size: | 10µg |
| Species: | Human |
| Target: | THAP3 |
| Synonyms: | THAP Domain Containing Apoptosis Associated Protein 3, THAP Domain-Containing Protein 3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The THAP3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 2mM DTT and 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMPKSCAA RQCCNRYSSR RKQLTFHRFP FSRPELLKEW VLNIGRGNFK PKQHTVICSE HFRPECFSAF GNRKNLKHNA VPTVFAFQDP TQQVRENTDP ASERGNASSS QKEKVLPEAG AGEDSPGRNM DTALEELQLP PNAEGHVKQV SPRRPQATEA VGRPTGPAGL RRTPNKQPSD HSYALLDLDS LKKKLFLTLK ENEKLRKRLQ AQRLVMRRMS SRLRACKGHQ GLQARLGPEQ QS |
THAP3 is an element of a THAP1/THAP3-HCFC1-OGT complex which is essential for the regulation of the transcriptional activity of RRM1. THAP3 is vastly produced in placenta, skeletal muscle and heart.
THAP3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-239) and having a molecular mass of 29.4kDa.THAP3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | THAP3: Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1p36.31 Molecular Function:protein binding |
| UniProt Code: | Q8WTV1 |
| NCBI GenInfo Identifier: | 29839586 |
| NCBI Gene ID: | 90326 |
| NCBI Accession: | Q8WTV1.1 |
| UniProt Secondary Accession: | Q8WTV1,Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2 Q9Y3H3, |
| UniProt Related Accession: | Q8WTV1 |
| Molecular Weight: | 27kDa |
| NCBI Full Name: | THAP domain-containing protein 3 |
| NCBI Synonym Full Names: | THAP domain containing 3 |
| NCBI Official Symbol: | THAP3 |
| NCBI Protein Information: | THAP domain-containing protein 3 |
| UniProt Protein Name: | THAP domain-containing protein 3 |
| Protein Family: | THAP domain-containing protein |
| UniProt Gene Name: | THAP3 |
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