Human TGFB3 Recombinant Protein (RPES1241)

(No reviews yet) Write a Review

제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.

주문
SKU:
RPES1241
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
€0.00
Frequently bought together:

Description

system_update_alt데이터시트

Human TGFB3 Recombinant Protein

Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3 becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3, mammals develop a deformity known as a cleft palate.

Product Name:Human TGFB3 Recombinant Protein (RPES1241)
Product Code:RPES1241
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Transforming growth factor beta-3,TGFB3,TGF-beta-3,Latency-associated peptide,LAP
Accession:P10600
Sequence:Ala301-Ser412(Tyr340Phe)
Fusion tag:
Activity:Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells.  The ED50 for this effect is 10-80 pg/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human/Mouse Transforming Growth Factor beta 3 is produced by our Mammalian expressionsystem and the target gene encoding Ala301-Ser412(Tyr340Phe) is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:12.7 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 4 mM HCl.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
View AllClose

Related Products