Human TGFB2 Recombinant Protein (RPES1225)

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SKU:
RPES1225
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human TGFB2 Recombinant Protein

Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).

Product Name:Human TGFB2 Recombinant Protein (RPES1225)
Product Code:RPES1225
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Transforming growth factor beta-2,TGFB2,Polyergin,G-TSF,Glioblastoma-derived T-cell suppressor factor,Cetermin,BSC-1 cell growth inhibitor,TGF-beta-2
Accession:P61812
Sequence:Ala303-Ser414
Fusion tag:
Activity:Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.3-1.5 ng/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:12.7 kDa
AP Mol Mass:12 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 4 mM HCl.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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