Human TCblR/8D6A Recombinant Protein (RPES1135)

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SKU:
RPES1135
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human TCblR/8D6A Recombinant Protein

CD320 antigen is also known as 8D6 antigen?FDC-signaling molecule 8D6?Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.

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