Human TCblR/8D6A Recombinant Protein (RPES1135)

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SKU:
RPES1135
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Human TCblR/8D6A Recombinant Protein

CD320 antigen is also known as 8D6 antigen?FDC-signaling molecule 8D6?Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.

Product Name:Human TCblR/8D6A Recombinant Protein (RPES1135)
Product Code:RPES1135
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:CD320 antigen,8D6 antigen,FDC-signaling molecule 8D6,FDC-SM-8D6,Transcobalamin receptor,TCblR,CD320
Accession: Q9NPF0
Sequence:Ser36-Val231
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Transcobalamin II Receptor is produced by our Mammalian expression system and the target gene encoding Ser36-Val231 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:21.1 kDa
AP Mol Mass:43 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 10mM Tris-Citrate,150mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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