Human STK16 Recombinant Protein (RPPB2652)

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SKU:
RPPB2652
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
STK16
Synonyms:
Serine/threonine-protein kinase 16
Synonyms:
Myristoylated and palmitoylated serine/threonine-protein kinase
Synonyms:
MPSK
Synonyms:
Protein kinase PKL12
Source:
Escherichia Coli
Uniprot:
O75716
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Description

Product Name:Human STK16 Recombinant Protein
Product Code:RPPB2652
Size:20µg
Species:Human
Target:STK16
Synonyms:Serine/threonine-protein kinase 16, Myristoylated and palmitoylated serine/threonine-protein kinase, MPSK, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, Tyrosine-protein kinase STK16, hPSK, STK16, MPSK1, PKL12, TSF1, KRCT.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:STK16 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMGHALC VCSRGTVIID NKRYLFIQKL GEGGFSYVDL VEGLHDGHFY ALKRILCHEQ QDREEAQREA DMHRLFNHPN ILRLVAYCLR ERGAKHEAWL LLPFFKRGTL WNEIERLKDK GNFLTEDQIL WLLLGICRGL EAIHAKGYAH RDLKPTNILL GDEGQPVLMD LGSMNQACIH VEGSRQALTL QDWAAQRCTI SYRAPELFSV QSHCVIDERT DVWSLGCVLY AMMFGEGPYD MVFQKGDSVA LAVQNQLSIP QSPRHSSALR QLLNSMMTVD PHQRPHIPLL LSQLEALQPP APGQHTTQI

Serine/threonine-protein kinase 16 (STK16) is a membrane-associated protein kinase which phosphorylates on serine and threonine residues. STK16 is involved in secretory vesicle trafficking or intracellular signaling. Furthermore, the STK16 protein may have a role in regulating stromal-epithelial interactions which occur during ductal morphogenesis in the mammary gland. STK16 can autophosphorylate on Tyr residue; it is however unclear whether STK16 has tyrosine-protein kinase toward other proteins. STK16 may also be involved in TGF-beta signaling.

STK16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 329 amino acids (1-305 a.a) and having a molecular mass of 37.2kDa.STK16 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:MPSK1: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage
UniProt Protein Details:

Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; EC 2.7.11.1; EC 2.7.10.2; Other group; NAK family

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cytoplasm

Molecular Function:protein binding; protein serine/threonine kinase activity

Biological Process: protein amino acid autophosphorylation

UniProt Code:O75716
NCBI GenInfo Identifier:46577677
NCBI Gene ID:8576
NCBI Accession:O75716.4
UniProt Secondary Accession:O75716,Q5U0F8, Q96KI2, Q9BUH4, Q9UEN3, Q9UP78, A8K9H9
UniProt Related Accession:O75716
Molecular Weight:34,656 Da
NCBI Full Name:Serine/threonine-protein kinase 16
NCBI Synonym Full Names:serine/threonine kinase 16
NCBI Official Symbol:STK16  
NCBI Official Synonym Symbols:KRCT; MPSK; TSF1; PKL12  
NCBI Protein Information:serine/threonine-protein kinase 16
UniProt Protein Name:Serine/threonine-protein kinase 16
UniProt Synonym Protein Names:Myristoylated and palmitoylated serine/threonine-protein kinase; MPSK; Protein kinase PKL12; TGF-beta-stimulated factor 1; TSF-1; Tyrosine-protein kinase STK16 (EC:2.7.10.2); hPSK
Protein Family:Serine/threonine-protein kinase
UniProt Gene Name:STK16  
UniProt Entry Name:STK16_HUMAN
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