Human STAT1 Recombinant Protein (RPES1886)

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SKU:
RPES1886
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human STAT1 Recombinant Protein

Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated; STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF); migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes; inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

Product Name:Human STAT1 Recombinant Protein (RPES1886)
Product Code:RPES1886
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1, CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91
Accession:P42224-2
Sequence:Met 1-Val712
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Signal Transducer and Activator of Transcription 1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:83.3 kDa
AP Mol Mass:85 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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