Human SSBP1 Recombinant Protein (RPPB4829)
- SKU:
- RPPB4829
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- SSBP1
- Synonyms:
- Mt-SSB
- mtSSB
- SOSS-B1
- SSBP
- Source:
- Escherichia Coli
- Uniprot:
- Q04837
Description
| Product Name: | Human SSBP1 Recombinant Protein |
| Product Code: | RPPB4829 |
| Size: | 20µg |
| Species: | Human |
| Target: | SSBP1 |
| Synonyms: | Mt-SSB, mtSSB, SOSS-B1, SSBP, PWP1-interacting protein 17, Single-stranded DNA-binding protein, mitochondrial. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | SSBP1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSESETTTS LVLERSLNRV HLLGRVGQDP VLRQVEGKNP VTIFSLATNE MWRSGDSEVY QLGDVSQKTT WHRISVFRPG LRDVAYQYVK KGSRIYLEGK IDYGEYMDKN NVRRQATTII ADNIIFLSDQ TKEKE |
Single-Stranded DNA Binding Protein 1 (SSBP) participates in mitochondrial biogenesis. SSBP binds preferentially and cooperatively to ss-DNA. The SSBP protein is involved in mitochondrial DNA replication and associates with mitochondrial DNA.
SSBP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (17-148 a.a.) and having a molecular mass of 17kDa.SSBP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SSBP1: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA. |
| UniProt Protein Details: | Protein type:RNA-binding; Mitochondrial Chromosomal Location of Human Ortholog: 7q34 Cellular Component: mitochondrion; mitochondrial matrix; nucleus Molecular Function:protein binding; chromatin binding; single-stranded DNA binding Biological Process: positive regulation of helicase activity; mitochondrion organization and biogenesis; organelle organization and biogenesis; DNA replication |
| NCBI Summary: | SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010] |
| UniProt Code: | Q04837 |
| NCBI GenInfo Identifier: | 417811 |
| NCBI Gene ID: | 6742 |
| NCBI Accession: | Q04837.1 |
| UniProt Related Accession: | Q04837 |
| Molecular Weight: | 148 |
| NCBI Full Name: | Single-stranded DNA-binding protein, mitochondrial |
| NCBI Synonym Full Names: | single-stranded DNA binding protein 1, mitochondrial |
| NCBI Official Symbol: | SSBP1 |
| NCBI Official Synonym Symbols: | SSBP; mtSSB; Mt-SSB; SOSS-B1 |
| NCBI Protein Information: | single-stranded DNA-binding protein, mitochondrial; PWP1-interacting protein 17 |
| UniProt Protein Name: | Single-stranded DNA-binding protein, mitochondrial |
| UniProt Synonym Protein Names: | PWP1-interacting protein 17 |
| UniProt Gene Name: | SSBP1 |
| UniProt Entry Name: | SSBP_HUMAN |
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