Human SIGLEC9/CD329 Recombinant Protein (RPES4997)

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SKU:
RPES4997
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human SIGLEC9/CD329 Recombinant Protein

Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils); and found in liver; fetal liver; bone marrow; placenta; spleen and in lower levels in skeletal muscle; fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Product Name:Human SIGLEC9/CD329 Recombinant Protein (RPES4997)
Product Code:RPES4997
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Sialic acid-binding Ig-like lectin 9,Siglec-9,CDw329,Protein FOAP-9,SIGLEC9
Accession:Q9Y336
Sequence:Gln18-Gly348(Lys100Glu;Ala315Glu)
Fusion tag:C-His
Activity:Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Approximately 93% will adhere after 5-10 mins incubation at 37 °C.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human SIGLEC9 is produced by our Mammalian expression system and the target gene encoding Gln18-Gly348(Lys100Glu;Ala315Glu) is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:36.9 kDa
AP Mol Mass:55-90 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS;2mMEDTA;ph7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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