Human SFRP5 Recombinant Protein (RPPB4657)

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SKU:
RPPB4657
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
SFRP5
Synonyms:
Secreted Frizzled-Related Protein 5
Synonyms:
SARP3
Synonyms:
Secreted Apoptosis Related Protein 3
Synonyms:
Secreted Apoptosis-Related Protein 3
Source:
Escherichia Coli
Uniprot:
Q5T4F7
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Description

Product Name:Human SFRP5 Recombinant Protein
Product Code:RPPB4657
Size:20µg
Species:Human
Target:SFRP5
Synonyms:Secreted Frizzled-Related Protein 5, SARP3, Secreted Apoptosis Related Protein 3, Secreted Apoptosis-Related Protein 3, Frizzled-Related Protein 1b, FRP-1b, SARP-3, SFRP-5, FRP1B, SFRP5.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:SFRP5 protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSEEYDYYG WQAEPLHGRS YSKPPQCLDI PADLPLCHTV GYKRMRLPNL LEHESLAEVK QQASSWLPLL AKRCHSDTQV FLCSLFAPVC LDRPIYPCRS LCEAVRAGCA PLMEAYGFPW PEMLHCHKFP LDNDLCIAVQ FGHLPATAPP VTKICAQCEM EHSADGLMEQ MCSSDFVVKM RIKEIKIENG DRKLIGAQKK KKLLKPGPLK RKDTKRLVLH MKNGAGCPCP QLDSLAGSFL VMGRKVDGQL LLMAVYRWDK KNKEMKFAVK FMFSYPCSLY YPFFYGAAEP H

Secreted Frizzled-Related Protein 5, also known as SFRP5, belongs to theSFRP family which includes a cysteine-rich domain homologous to the putativeWnt-binding site of Frizzled proteins. SFRPs perform like soluble modulatorsof  Wnt signaling. SFRP5 & SFRP1 areimplicated in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in theretinal pigment epithelium, as well as moderately expressed in the pancreas. 

SFRP5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 311 amino acids (30-317 a.a) and having a molecular mass of 35kDa.SFRP5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Code:Q5T4F7
NCBI GenInfo Identifier:188528609
NCBI Gene ID:6425
NCBI Accession:NP_003006.2
UniProt Secondary Accession:Q5T4F7,O14780, Q86TH7,
UniProt Related Accession:Q5T4F7
Molecular Weight:35,563 Da
NCBI Full Name:secreted frizzled-related protein 5
NCBI Synonym Full Names:secreted frizzled-related protein 5
NCBI Official Symbol:SFRP5  
NCBI Official Synonym Symbols:SARP3  
NCBI Protein Information:secreted frizzled-related protein 5; FRP-1b; SARP-3; sFRP-5; frizzled-related protein 1b; secreted apoptosis related protein 3; secreted apoptosis-related protein 3
UniProt Protein Name:Secreted frizzled-related protein 5
UniProt Synonym Protein Names:Frizzled-related protein 1b; FRP-1b; Secreted apoptosis-related protein 3
Protein Family:Secreted frizzled-related protein
UniProt Gene Name:SFRP5  
UniProt Entry Name:SFRP5_HUMAN
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