Human SCGN Recombinant Protein (RPPB4595)
- SKU:
- RPPB4595
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- SCGN
- Synonyms:
- SCGN
- EF-hand calcium binding protein
- Setagin
- SEGN
- Source:
- Escherichia Coli
- Uniprot:
- O76038
Description
| Product Name: | Human SCGN Recombinant Protein |
| Product Code: | RPPB4595 |
| Size: | 10µg |
| Species: | Human |
| Target: | SCGN |
| Synonyms: | SCGN, EF-hand calcium binding protein, Setagin, SEGN, CALBL, SECRET, DJ501N12.8, Secretagogin. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless liquid formulation. |
| Formulation: | SCGN His-Tag (1mg/ml) protein is supplied in 20mM Tris HCl pH-8, 1mM DTT, 0.1M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MDSSREPTLG RLDAAGFWQV WQRFDADEKG YIEEKELDAF FLHMLMKLGT DDTVMKANLH KVKQQFMTTQ DASKDGRIRM KELAGMFLSE DENFLLLFRR ENPLDSSVEF MQIWRKYDAD SSGFISAAEL RNFLRDLFLH HKKAISEAKL EEYTGTMMKI FDRNKDGRLD LNDLARILAL QENFLLQFKM DACSTEERKR DFEKIFAYYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL RHCDVNKDGK IQKSELALCL GLKINP |
SCGN is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. Secretagogin is involved in KCL-stimulated calcium flux and cell proliferation.Secretagogin plays a role in human non-functional pituitary adenomas.
SCGN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 296 amino acids (1-276 a.a.) and having a molecular mass of 34.2kDa. SCGN is fused to a 20 amino acid His tag at N-terminus and purified by standard chromatography techniques.
| UniProt Protein Function: | SCGN: |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p22.3-p22.1 Cellular Component: cytosol; neuron projection; nucleus; synapse Molecular Function:calcium ion binding Biological Process: cytosolic calcium ion homeostasis |
| NCBI Summary: | The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O76038 |
| NCBI GenInfo Identifier: | 21264511 |
| NCBI Gene ID: | 10590 |
| NCBI Accession: | O76038.2 |
| UniProt Secondary Accession: | O76038,Q5VV44, Q96QV7, Q9UJF6, A8K0B2, |
| UniProt Related Accession: | O76038 |
| Molecular Weight: | 32,040 Da |
| NCBI Full Name: | Secretagogin |
| NCBI Synonym Full Names: | secretagogin, EF-hand calcium binding protein |
| NCBI Official Symbol: | SCGN |
| NCBI Official Synonym Symbols: | SEGN; CALBL; SECRET; setagin; DJ501N12.8 |
| NCBI Protein Information: | secretagogin |
| UniProt Protein Name: | Secretagogin |
| Protein Family: | Secretagogin |
| UniProt Gene Name: | SCGN |
| UniProt Entry Name: | SEGN_HUMAN |
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