Human SAA2/Serum Amyloid A2 Recombinant Protein (RPES5036)

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SKU:
RPES5036
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human SAA2/Serum Amyloid A2 Recombinant Protein

Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.

Product Name:Human SAA2/Serum Amyloid A2 Recombinant Protein (RPES5036)
Product Code:RPES5036
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:SAA, SAA2, Serum Amyloid A2
Accession:P0DJI9
Sequence:Arg19-Tyr122
Fusion tag:N-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Serum amyloid A-2 protein is produced by our E.coli expression system and the target gene encoding Arg19-Tyr122 is expressed with a 6His tag at the N-terminus.
Purity:> 90% as determined by reducing SDS-PAGE.
Mol Mass:13.2 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mMPB,150mMNaCl,pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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