Human S100A16 Recombinant Protein (RPPB4552)
- SKU:
- RPPB4552
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- S100A16
- Synonyms:
- Protein S100-A16
- Aging-associated gene 13 protein
- Protein S100-F
- S100 calcium-binding protein A16
- Source:
- Escherichia Coli
- Uniprot:
- Q96FQ6
Description
| Product Name: | Human S100A16 Recombinant Protein |
| Product Code: | RPPB4552 |
| Size: | 20µg |
| Species: | Human |
| Target: | S100A16 |
| Synonyms: | Protein S100-A16, Aging-associated gene 13 protein, Protein S100-F, S100 calcium-binding protein A16, S100A16, S100F, AAG13, DT1P1A7, MGC17528. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | S100A16 (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 40% glycerol and 0.2M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSDCYTELEK AVIVLVENFY KYVSKYSLVK NKISKSSFRE MLQKELNHML SDTGNRKAAD KLIQNLDANH DGRISFDEYW TLIGGITGPI AKLIHEQEQQ SSS |
S100A16 belongs to the S100 protein super family containing calcium-binding EF-hand motifs. S100 proteins are cell and tissue specific and are engaged in various intra and extracellular processes through interacting with specific target proteins. The S100A16 expression is astrocyte-specific. S100A16 accumulates within nucleoli and translocates to the cytoplasm in reaction to Ca(2+) stimulation. S100A16 physically interacts with tumor suppressor protein p53 (which is a known inhibitor of adipogenesis) as determined Immunoprecipitation analysis.
S100A16 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 123 amino acids (1-103 a.a.) and having a molecular mass of 13.9kDa.S100A16 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | S100A16: Calcium-binding protein. Binds one calcium ion per monomer. Belongs to the S-100 family. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cytosol; nucleolus; plasma membrane Molecular Function:calcium ion binding; protein binding; protein homodimerization activity Biological Process: response to calcium ion |
| UniProt Code: | Q96FQ6 |
| NCBI GenInfo Identifier: | 20178113 |
| NCBI Gene ID: | 140576 |
| NCBI Accession: | Q96FQ6.1 |
| UniProt Secondary Accession: | Q96FQ6,Q5RHS6, A8K439, D3DV52, |
| UniProt Related Accession: | Q96FQ6 |
| Molecular Weight: | 11,801 Da |
| NCBI Full Name: | Protein S100-A16 |
| NCBI Synonym Full Names: | S100 calcium binding protein A16 |
| NCBI Official Symbol: | S100A16 |
| NCBI Official Synonym Symbols: | AAG13; S100F; DT1P1A7 |
| NCBI Protein Information: | protein S100-A16 |
| UniProt Protein Name: | Protein S100-A16 |
| UniProt Synonym Protein Names: | Aging-associated gene 13 protein; Protein S100-F; S100 calcium-binding protein A16 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A16 |
| UniProt Entry Name: | S10AG_HUMAN |
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