Human S100A10 Recombinant Protein (RPPB4546)

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SKU:
RPPB4546
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
S100A10
Synonyms:
Protein S100-A10
Synonyms:
S100 calcium-binding protein A10
Synonyms:
Calpactin-1 light chain
Synonyms:
Calpactin I light chain
Source:
Escherichia Coli
Uniprot:
P60903
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Description

Product Name:Human S100A10 Recombinant Protein
Product Code:RPPB4546
Size:10µg
Species:Human
Target:S100A10
Synonyms:Protein S100-A10, S100 calcium-binding protein A10, Calpactin-1 light chain, Calpactin I light chain, p10 protein, p11, Cellular ligand of annexin II, S100A10, ANX2LG, CAL1L, CLP11, 42C, p10, GP11, ANX2L, Ca[1], MGC111133.
Source:Escherichia Coli
Formulation:S100-A10 is supplied in 1xPBS and 50% Glycerol.
Stability:Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.2 bands on Western blot at 15.3 and 30.6 kDa, respectively representing monomeric and dimeric form.

S100A10 is a member of the S100 family of proteins contains two EF-hand calcium-binding motifs and is thought to be involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. S100A10 may function in exocytosis and endocytosis.

S100A10 Human Recombinant also called Calpactin light chain is expressed in E. coli having a molecular weight of 15.3kDa fused to an amino terminal hexahistidine tag.

UniProt Protein Function:S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.
UniProt Protein Details:

Protein type:Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extrinsic to plasma membrane; lipid raft

Molecular Function:protein binding; protein homodimerization activity; calcium ion binding; lipid binding

Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding

NCBI Summary:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
UniProt Code:P60903
NCBI GenInfo Identifier:46397706
NCBI Gene ID:6281
NCBI Accession:P60903.2
UniProt Related Accession:P60903
Molecular Weight:11kDa
NCBI Full Name:Protein S100-A10
NCBI Synonym Full Names:S100 calcium binding protein A10
NCBI Official Symbol:S100A10  
NCBI Official Synonym Symbols:42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG  
NCBI Protein Information:protein S100-A10
UniProt Protein Name:Protein S100-A10
UniProt Synonym Protein Names:Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family:Protein
UniProt Gene Name:S100A10  
UniProt Entry Name:S10AA_HUMAN
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