Human RPP30 Recombinant Protein (RPPB2259)
- SKU:
- RPPB2259
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- RPP30
- Synonyms:
- Ribonuclease P protein subunit p30
- RNaseP protein p30
- RNase P subunit 2
- RPP30
- Source:
- Escherichia Coli
- Uniprot:
- P78346
Description
| Product Name: | Human RPP30 Recombinant Protein |
| Product Code: | RPPB2259 |
| Size: | 20µg |
| Species: | Human |
| Target: | RPP30 |
| Synonyms: | Ribonuclease P protein subunit p30, RNaseP protein p30, RNase P subunit 2, RPP30, RNASEP2, TSG15, FLJ38491, RP11-320F15.1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RPP30 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 5mM DTT, 200mM NaCl and 1mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAVFADL DLRAGSDLKA LRGLVETAAH LGYSVVAINH IVDFKEKKQE IEKPVAVSEL FTTLPIVQGK SRPIKILTRL TIIVSDPSHC NVLRATSSRA RLYDVVAVFP KTEKLFHIAC THLDVDLVCI TVTEKLPFYF KRPPINVAID RGLAFELVYS PAIKDSTMRR YTISSALNLM QICKGKNVII SSAAERPLEI RGPYDVANLG LLFGLSESDA KAAVSTNCRA ALLHGETRKT AFGIISTVKK PRPSEGDEDC LPASKKAKCE G |
Ribonuclease P protein subunit p30 (RPP30) is a member of the eukaryotic/archaeal RNase P protein component 3 family. RPP30 is component of ribonuclease P, which is a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Ribonuclease P (RNase P) is small nuclear ribonucleoprotein (snRNPs) which acts on RNA substrates in vitro. In addition, RNase P which accumulate in the nucleolus, have a similar RNA component and several protein subunits in common.
RPP30 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 291 amino acids (1-268 a.a.) and having a molecular mass of 31.8kDa. The RPP30 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPP30: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family. |
| UniProt Protein Details: | Protein type:EC 3.1.26.5; Nucleolus; Ribonuclease Chromosomal Location of Human Ortholog: 10q23.31 Cellular Component: nucleolar ribonuclease P complex; nucleoplasm; nucleus Molecular Function:protein binding; ribonuclease P activity; RNA binding Biological Process: rRNA processing; tRNA 5'-leader removal; tRNA processing |
| UniProt Code: | P78346 |
| NCBI GenInfo Identifier: | 13124514 |
| NCBI Gene ID: | 10556 |
| NCBI Accession: | P78346.1 |
| UniProt Secondary Accession: | P78346,B2R799, E9PB02, |
| UniProt Related Accession: | P78346 |
| Molecular Weight: | 29kDa |
| NCBI Full Name: | Ribonuclease P protein subunit p30 |
| NCBI Synonym Full Names: | ribonuclease P/MRP subunit p30 |
| NCBI Official Symbol: | RPP30 |
| NCBI Official Synonym Symbols: | TSG15 |
| NCBI Protein Information: | ribonuclease P protein subunit p30 |
| UniProt Protein Name: | Ribonuclease P protein subunit p30 |
| UniProt Synonym Protein Names: | RNase P subunit 2 |
| Protein Family: | Ribonuclease P protein |
| UniProt Gene Name: | RPP30 |
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