Human RNF114 Recombinant Protein (RPPB4481)

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SKU:
RPPB4481
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
RNF114
Synonyms:
E3 ubiquitin-protein ligase RNF114
Synonyms:
RING finger protein 114
Synonyms:
Zinc finger protein 228
Synonyms:
Zinc finger protein 313
Source:
Escherichia Coli
Uniprot:
Q9Y508
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Description

Product Name:Human RNF114 Recombinant Protein
Product Code:RPPB4481
Size:20µg
Species:Human
Target:RNF114
Synonyms:E3 ubiquitin-protein ligase RNF114, RING finger protein 114, Zinc finger protein 228, Zinc finger protein 313, RNF114, ZNF228, ZNF313, PSORS12.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RNF114 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAAQQRD CGGAAQLAGP AAEADPLGRF TCPVCLEVYE KPVQVPCGHV FCSACLQECL KPKKPVCGVC RSALAPGVRA VELERQIEST ETSCHGCRKN FFLSKIRSHV ATCSKYQNYI MEGVKATIKD ASLQPRNVPN RYTFPCPYCP EKNFDQEGLV EHCKLFHSTD TKSVVCPICA SMPWGDPNYR SANFREHIQR RHRFSYDTFV DYDVDEEDMM NQVLQRSIID Q

Ring Finger Protein 114 (RNF114) is expressed in various tissues, including skin, CD4 lymphocytes and dendritic cells. RNF114, which contains 1 RING-type zinc finger, takes part in spermatogenesis.

RNF114 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 251 amino acids (1-228 a.a) and having a molecular mass of 28.1kDa.RNF114 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ZNF313: May play a role in spermatogenesis. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; Ubiquitin ligase; Transcription factorChromosomal Location of Human Ortholog: 20q13.13Cellular Component: cytosol; intracellularMolecular Function: ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activityBiological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9Y508
NCBI GenInfo Identifier:8923898
NCBI Gene ID:55905
NCBI Accession:NP_061153.1
UniProt Secondary Accession:Q9Y508,Q6N0B0, B2RDQ9, B4DWY5, E1P627
UniProt Related Accession:Q9Y508
Molecular Weight:21,004 Da
NCBI Full Name:E3 ubiquitin-protein ligase RNF114
NCBI Synonym Full Names:ring finger protein 114
NCBI Official Symbol:RNF114  
NCBI Official Synonym Symbols:ZNF313; PSORS12  
NCBI Protein Information:E3 ubiquitin-protein ligase RNF114
UniProt Protein Name:E3 ubiquitin-protein ligase RNF114
UniProt Synonym Protein Names:RING finger protein 114; Zinc finger protein 228; Zinc finger protein 313
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:RNF114  
UniProt Entry Name:RN114_HUMAN
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