Human Ribonuclease 3/RNASE3 Recombinant Protein (RPES3913)

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SKU:
RPES3913
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Ribonuclease 3/RNASE3 Recombinant Protein

Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Product Name:Human Ribonuclease 3/RNASE3 Recombinant Protein (RPES3913)
Product Code:RPES3913
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Eosinophil Cationic Protein, ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3
Accession:P12724
Sequence:Arg28-Ile160
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ribonuclease 3 is produced by our Mammalian expression system and the target gene encoding Arg28-Ile160 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:16.6 kDa
AP Mol Mass:25 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,1mMDTT,10%Glycerol,pH7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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