Human RHEB Recombinant Protein (RPES1442)
- SKU:
- RPES1442
- Product type:
- Recombinant Protein
- Host species:
- Baculovirus-Insect Cells
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human RHEB Recombinant Protein
RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase superfamily and encodes a lipid-anchored; cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form; and farnesylation of RHEB is required for this activity. Three pseudogenes have been mapped; two on chromosome 10 and one on chromosome 22.
Product Name: | Human RHEB Recombinant Protein (RPES1442) |
Product Code: | RPES1442 |
Size: | 50µg |
Species: | Human |
Expressed Host: | Baculovirus-Insect Cells |
Synonyms: | GTP-Binding Protein Rheb, Ras Homolog Enriched in Brain, RHEB, RHEB2 |
Accession: | Q15382 |
Sequence: | Met 1-Cys181 |
Fusion tag: | N-His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | A DNA sequence encoding the human RHEB (Q15382)(Met1-Cys181) was fused with a polyhistide tag at the N-terminus. |
Purity: | > 85 % as determined by reducing SDS-PAGE. |
Mol Mass: | 22.4 kDa |
AP Mol Mass: | 21 kDa |
Formulation: | Lyophilized from sterile 20mM Tris; 500mM NaCl; 10% gly; pH 7.4 |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |