Human RHEB Recombinant Protein (RPES1442)

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SKU:
RPES1442
Product type:
Recombinant Protein
Host species:
Baculovirus-Insect Cells
Reactivity:
Human
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Description

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Human RHEB Recombinant Protein

RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase superfamily and encodes a lipid-anchored; cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form; and farnesylation of RHEB is required for this activity. Three pseudogenes have been mapped; two on chromosome 10 and one on chromosome 22.

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