Human RCN3 Recombinant Protein (RPPB4431)

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SKU:
RPPB4431
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
RCN3
Synonyms:
Reticulocalbin-3
Synonyms:
EF-hand calcium-binding protein RLP49
Synonyms:
RCN3
Synonyms:
RLP49
Source:
Escherichia Coli
Uniprot:
Q96D15
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Description

Product Name:Human RCN3 Recombinant Protein
Product Code:RPPB4431
Size:20µg
Species:Human
Target:RCN3
Synonyms:Reticulocalbin-3, EF-hand calcium-binding protein RLP49, RCN3, RLP49.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RCN3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMKPSPD AGPHGQGRVH QAAPLSDAPH DDAHGNFQYD HEAFLGREVA KEFDQLTPEE SQARLGRIVD RMDRAGDGDG WVSLAELRAW IAHTQQRHIR DSVSAAWDTY DTDRDGRVGW EELRNATYGH YAPGEEFHDV EDAETYKKML ARDERRFRVA DQDGDSMATR EELTAFLHPE EFPHMRDIVI AETLEDLDRN KDGYVQVEEY IADLYSAEPG EEEPAWVQTE RQQFRDFRDL NKDGHLDGSE VGHWVLPPAQ DQPLVEANHL LHESDTDKDG RLSKAEILGN WNMFVGSQAT NYGEDLTRHH DEL

Reticulocalbin 3 (RCN3) belongs to the CREC (cab45/reticulocalbin/ ERC45/calumenin) family. RCN3 contains 5 Arg-Xaa-Xaa-Arg motifs, which function as target sequences of SPCs (subtilisin-like proprotein convertases), which is a family of serine endoproteases that proteolytically activate proproteins. The synthesis of PACE4 is induced by association and coexpression with RCN3.

RCN3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 333 amino acids (21-328 a.a) and having a molecular mass of 37.9kDa.RCN3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:RCN3: Belongs to the CREC family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 19q13.33Cellular Component: endoplasmic reticulum lumenMolecular Function: protein binding; calcium ion binding
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q96D15
NCBI GenInfo Identifier:28626510
NCBI Gene ID:57333
NCBI Accession:NP_065701.2
UniProt Secondary Accession:Q96D15,Q9HBZ8
UniProt Related Accession:Q96D15
Molecular Weight:37,493 Da
NCBI Full Name:reticulocalbin-3
NCBI Synonym Full Names:reticulocalbin 3, EF-hand calcium binding domain
NCBI Official Symbol:RCN3  
NCBI Official Synonym Symbols:RLP49  
NCBI Protein Information:reticulocalbin-3; reticulocabin; EF-hand calcium-binding protein RLP49
UniProt Protein Name:Reticulocalbin-3
UniProt Synonym Protein Names:EF-hand calcium-binding protein RLP49
Protein Family:Reticulocalbin
UniProt Gene Name:RCN3  
UniProt Entry Name:RCN3_HUMAN
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