Human RBP2 Recombinant Protein (RPPB0935)
- SKU:
- RPPB0935
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- RBP2
- Synonyms:
- CRABP-II
- CRBP2
- CRBPII
- RBPC2
- Source:
- Escherichia Coli
- Uniprot:
- P50120
Description
| Product Name: | Human RBP2 Recombinant Protein |
| Product Code: | RPPB0935 |
| Size: | 20µg |
| Species: | Human |
| Target: | RBP2 |
| Synonyms: | CRABP-II, CRBP2, CRBPII, RBPC2, Retinol-binding protein 2, Cellular retinol-binding protein II, RBP2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RBP2 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMTRDQN GTWEMESNEN FEGYMKALDI DFATRKIAVR LTQTKVIDQD GDNFKTKTTS TFRNYDVDFT VGVEFDEYTK SLDNRHVKAL VTWEGDVLVC VQKGEKENRG WKQWIEGDKL YLELTCGDQV CRQVFKKK |
Retinol Binding Protein-2 (RBP2) which is present in the small intestinal epithelium takes part in the uptake and intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin essential for growth, reproduction, differentiation of epithelial tissues, and vision. RBP2 moderates the supply of retinoic acid to the nuclei of endometrial cells throughout the menstrual cycle.
RBP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (1-134 a.a.) and having a molecular mass of 18kDa. RBP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RBP2: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q23 Cellular Component: cytosol Molecular Function:retinoid binding Biological Process: epidermis development; retinoid metabolic process |
| NCBI Summary: | This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50120 |
| NCBI GenInfo Identifier: | 62297500 |
| NCBI Gene ID: | 5948 |
| NCBI Accession: | P50120.3 |
| UniProt Secondary Accession: | P50120,Q6ISQ9, Q6ISS7, A8K7G3, |
| UniProt Related Accession: | P50120 |
| Molecular Weight: | 16kDa |
| NCBI Full Name: | Retinol-binding protein 2 |
| NCBI Synonym Full Names: | retinol binding protein 2 |
| NCBI Official Symbol: | RBP2 |
| NCBI Official Synonym Symbols: | CRBP2; RBPC2; CRBPII; CRABP-II |
| NCBI Protein Information: | retinol-binding protein 2 |
| UniProt Protein Name: | Retinol-binding protein 2 |
| UniProt Synonym Protein Names: | Cellular retinol-binding protein II; CRBP-II |
| Protein Family: | RNA-binding protein |
| UniProt Gene Name: | RBP2 |
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