Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo. However, deficit or excess of either one of these substances can cause early embryo mortality or developmental malformations. Regulation of transport and metabolism of retinol necessary for a successful pregnancy is accomplished via RBP. Retinol binding proteins have been identified within the uterus, embryo, and extraembryonic tissue of the bovine, ovine, and porcine, clearly indicating that RBP plays a role in proper retinol exposure to the embryo and successful transport at the maternal-fetal interface.
Product Name:
Human RBP2 Recombinant Protein (RPES3846)
Product Code:
RPES3846
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Retinol-binding protein 2, Cellular retinol-binding protein II, CRBP-II, RBP2, CRBP2
Accession:
P50120
Sequence:
Met 1-Lys134
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Retinol-binding Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys134 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.7 kDa
AP Mol Mass:
15-17 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
