Human RAB24 Recombinant Protein (RPPB4354)
- SKU:
- RPPB4354
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- RAB24
- Synonyms:
- RAB24 member RAS oncogene family
- ras-related protein Rab-24
- Source:
- Escherichia Coli
- Uniprot:
- Q969Q5
Description
| Product Name: | Human RAB24 Recombinant Protein |
| Product Code: | RPPB4354 |
| Size: | 20µg |
| Species: | Human |
| Target: | RAB24 |
| Synonyms: | RAB24 member RAS oncogene family, ras-related protein Rab-24. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The RAB24 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl, 0.1M EDTA and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH |
RAB24 is a member of the small GTPase superfamily which regulates intracellular protein transferring, nonetheless the specific role of RAB24 has not yet been revealed. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures which suggests connection to autophagy-related courses. RAB24 demonstrates uncommon characteristics such as low intrinsic GTPase activity, and is incompetently prenylated when compared with other Rab proteins indicates that RAB24 has a distinctive part in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope.
RAB24 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-203) and having a molecular mass of 25.7 kDa.RAB24 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | May be involved in autophagy-related processes. |
| NCBI Summary: | RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009] |
| UniProt Code: | Q969Q5 |
| NCBI GenInfo Identifier: | 72534833 |
| NCBI Gene ID: | 53917 |
| NCBI Accession: | NP_001026847.1 |
| UniProt Secondary Accession: | Q969Q5,Q7Z4Z7, |
| UniProt Related Accession: | Q969Q5 |
| Molecular Weight: | 23,124 Da |
| NCBI Full Name: | ras-related protein Rab-24 |
| NCBI Synonym Full Names: | RAB24, member RAS oncogene family |
| NCBI Official Symbol: | RAB24 |
| NCBI Protein Information: | ras-related protein Rab-24 |
| UniProt Protein Name: | Ras-related protein Rab-24 |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB24 |
| UniProt Entry Name: | RAB24_HUMAN |
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