Human PSA/KLK3 Recombinant Protein (RPES2968)

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SKU:
RPES2968
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human PSA/KLK3 Recombinant Protein

KLK3; also known as APS; is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+; 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins; which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Product Name:Human PSA/KLK3 Recombinant Protein (RPES2968)
Product Code:RPES2968
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:APS,Hk3,KLK2A1,PSA,Prostate-Specific Antigen, PSA, Gamma-Seminoprotein, Seminin, Kallikrein-3, P-30 Antigen, Semenogelase,
Accession:P07288
Sequence:Ile25-Pro261
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Kallikrein-3/Prostate-specific antigen is produced by our Mammalian expression system and the target gene encoding Ile25-Pro261 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:27.1 kDa
AP Mol Mass:35 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHcl; 150mM NaCl;1mM CaCl2;pH7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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