Human PRSS3 Recombinant Protein (RPPB2189)

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SKU:
RPPB2189
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
PRSS3
Synonyms:
Protease Serine 3 (Mesotrypsin)
Synonyms:
Protease Serine 4 (Trypsin 4
Synonyms:
Brain)
Synonyms:
Brain Trypsinogen
Source:
Escherichia Coli
Uniprot:
P35030
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Description

Product Name:Human PRSS3 Recombinant Protein
Product Code:RPPB2189
Size:20µg
Species:Human
Target:PRSS3
Synonyms:Protease Serine 3 (Mesotrypsin), Protease Serine 4 (Trypsin 4, Brain), Brain Trypsinogen, Mesotrypsinogen, Trypsin III, Trypsinogen IV, Trypsinogen 5, Pancreatic Trypsinogen III, MTG, TRY3, PRSS4, T9, EC 3.4.21.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The PRSS3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSIVGGYTC EENSLPYQVS LNSGSHFCGG SLISEQWVVS AAHCYKTRIQ VRLGEHNIKV LEGNEQFINA AKIIRHPKYN RDTLDNDIML IKLSSPAVIN ARVSTISLPT APPAAGTECL ISGWGNTLSF GADYPDELKC LDAPVLTQAE CKASYPGKIT NSMFCVGFLE GGKDSCQRDS GGPVVCNGQL QGVVSWGHGC AWKNRPGVYT KVYNYVDWIK DTIAANS

PRSS3 is a trypsinogen, and a member of the trypsin family of serine proteases. PRSS3 is expressed in the pancreas and brain and is unaffected by common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is restricted to the locus of T cell receptor beta variable orphans on chromosome 9. 4 different isoforms encoded by 4 transcript variants were identified for this gene.

PRSS3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 247 amino acids (81-304) and having a molecular mass of 26.0kDa.PRSS3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
UniProt Protein Details:
NCBI Summary:This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]
UniProt Code:P35030
NCBI GenInfo Identifier:209572698
NCBI Gene ID:5646
NCBI Accession:P35030.2
UniProt Secondary Accession:P35030,P15951, Q15665, Q5VXV0, Q6ISJ4, Q9UQV3, A8CED1 A8CED3, A9Z1Y4, E7ES07
UniProt Related Accession:P35030
Molecular Weight:25,924 Da
NCBI Full Name:Trypsin-3
NCBI Synonym Full Names:protease, serine 3
NCBI Official Symbol:PRSS3  
NCBI Official Synonym Symbols:T9; MTG; TRY3; TRY4; PRSS4  
NCBI Protein Information:trypsin-3
UniProt Protein Name:Trypsin-3
UniProt Synonym Protein Names:Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV
Protein Family:
UniProt Gene Name:PRSS3  
UniProt Entry Name:TRY3_HUMAN
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