Human PRPS2 Recombinant Protein (RPPB2638)
- SKU:
- RPPB2638
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- PRPS2
- Synonyms:
- Phosphoribosyl Pyrophosphate Synthetase 2
- PhosphoribosylPyrophosphate Synthase II
- Ribose-Phosphate Diphosphokinase 2
- EC 2761
- Source:
- Escherichia Coli
- Uniprot:
- P11908
Description
| Product Name: | Human PRPS2 Recombinant Protein |
| Product Code: | RPPB2638 |
| Size: | 20µg |
| Species: | Human |
| Target: | PRPS2 |
| Synonyms: | Phosphoribosyl Pyrophosphate Synthetase 2, PhosphoribosylPyrophosphate Synthase II, Ribose-Phosphate Diphosphokinase 2, EC 2.7.6.1, PRS-II,Ribose-Phosphate Pyrophosphokinase 2, PPRibP Synthetase , PRS II, PPRibP, PRSII,Ribose-phosphate pyrophosphokinase 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PRPS2 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4), 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMPNIVLF SGSSHQDLSQ RVADRLGLEL GKVVTKKFSN QETSVEIGESVRGEDVYIIQ SGCGEINDNL MELLIMINAC KIASSSRVTA VIPCFPYARQ DKKDKVGESR APISAKLVANMLSVAGADHI ITMDLHASQI QGFFDIPVDN LYAEPAVLQW IRENIAEWKN CIIVSPDAGG AKRVTSIADRLNVEFALIHK ERKKANEVDR MVLVGDVKDR VAILVDDMAD TCGTICHAAD KLLSAGATKV YAILTHGIFSGPAISRINNA AFEAVVVTNT IPQEDKMKHC TKIQVIDISM ILAEAIRRTH NGESVSYLFS HVPL |
Phosphoribosyl Pyrophosphate Synthetase 2, also known as PRPS2 is a member of the ribose-phosphate pyrophosphokinase family. PRPS2 catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate.
PRPS2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 344 amino acids (1-321 a.a) andhaving a molecular mass of 37.4kDa.PRPS2 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PRPS2: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other; Carbohydrate Metabolism - pentose phosphate pathway; EC 2.7.6.1; Nucleotide Metabolism - purine Chromosomal Location of Human Ortholog: Xp22.2 Molecular Function:ATP binding; identical protein binding; protein binding; protein homodimerization activity; ribose phosphate diphosphokinase activity Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| NCBI Summary: | This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P11908 |
| NCBI GenInfo Identifier: | 125583 |
| NCBI Gene ID: | 5634 |
| NCBI Accession: | P11908.2 |
| UniProt Secondary Accession: | P11908,Q0VDH9, Q0VDI0, Q15245, Q2TAK7, |
| UniProt Related Accession: | P11908 |
| Molecular Weight: | 35,054 Da |
| NCBI Full Name: | Ribose-phosphate pyrophosphokinase 2 |
| NCBI Synonym Full Names: | phosphoribosyl pyrophosphate synthetase 2 |
| NCBI Official Symbol: | PRPS2 |
| NCBI Official Synonym Symbols: | PRSII |
| NCBI Protein Information: | ribose-phosphate pyrophosphokinase 2 |
| UniProt Protein Name: | Ribose-phosphate pyrophosphokinase 2 |
| UniProt Synonym Protein Names: | PPRibP; Phosphoribosyl pyrophosphate synthase II; PRS-II |
| UniProt Gene Name: | PRPS2 |
| UniProt Entry Name: | PRPS2_HUMAN |
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