Human PRKAR1A Recombinant Protein (RPES4062)

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SKU:
RPES4062
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human PRKAR1A Recombinant Protein

cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.

Product Name:Human PRKAR1A Recombinant Protein (RPES4062)
Product Code:RPES4062
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Tissue-specific extinguisher 1,TSE1
Accession:P10644
Sequence:Glu2-Val381
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human cAMP-dependent protein kinase regulatory type I-alpha is produced by our Mammalian expression system and the target gene encoding Glu2-Val381 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:44.0 kDa
AP Mol Mass:50 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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