Human PREP Recombinant Protein (RPPB2183)
- SKU:
- RPPB2183
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- PREP
- Synonyms:
- Prolyl Endopeptidase
- Post-Proline Cleaving Enzyme
- EC342126
- PEP
- Source:
- Escherichia Coli
- Uniprot:
- P48147
Description
| Product Name: | Human PREP Recombinant Protein |
| Product Code: | RPPB2183 |
| Size: | 10µg |
| Species: | Human |
| Target: | PREP |
| Synonyms: | Prolyl Endopeptidase, Post-Proline Cleaving Enzyme, EC3.4.21.26, PEP, PE, DJ355L5.1 (Prolyl Endopeptidase), Prolyl Oligopeptidase, Prolylendopeptidase. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | PREP protein solution (0.25mg/ml) containing PBS buffer (pH 7.4), 30% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLSLQYP DVYRDETAVQ DYHGHKICDP YAWLEDPDSE QTKAFVEAQNKITVPFLEQC PIRGLYKERM TELYDYPKYS CHFKKGKRYF YFYNTGLQNQ RVLYVQDSLE GEARVFLDPNILSDDGTVAL RGYAFSEDGE YFAYGLSASG SDWVTIKFMKVDGAKELPDV LERVKFSCMA WTHDGKGMFY NSYPQQDGKS DGTETSTNLHQKLYYHVLGT DQSEDILCAE FPDEPKWMGG AELSDDGRYV LLSIREGCDP VNRLWYCDLQ QESSGIAGILKWVKLIDNFE GEYDYVTNEG TVFTFKTNRQ SPNYRVINID FRDPEESKWK VLVPEHEKDVLEWIACVRSN FLVLCYLHDV KNILQLHDLT TGALLKTFPL DVGSIVGYSGQKKDTEIFYQ FTSFLSPGII YHCDLTKEEL EPRVFREVTV KGIDASDYQT VQIFYPSKDG TKIPMFIVHKKGIKLDGSHP AFLYGYGGFN ISITPNYSVS RLIFVRHMGG ILAVANIRGG GEYGETWHKGGILANKQNCF DDFQCAAEYL IKEGYTSPKR LTINGGSNGG LLVAACANQRPDLFGCVIAQ VGVMDMLKFH KYTIGHAWTT DYGCSDSKQH FEWLVKYSPL HNVKLPEADD IQYPSMLLLT ADHDDRVVPLHSLKFIATLQ YIVGRSRKQS NPLLIHVDTK AGHGAGKPTA KVIEEVSDMFAFIARCLNVD WIP |
Prolyl Endopeptidase , also known as PREP is a cytosolic prolylendopeptidase which cleaves peptide bonds on the C-terminal side of prolyl residueswithin peptides which are up to about 30 a.a long. In addition, Prolyl endopeptidaseshave been shown to be implicated in the maturation and degradation of peptidehormones and neuropeptides.
PREP Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 733 amino acids (1-710 a.a) andhaving a molecular mass of 83.1kDa.PREP is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PREP: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Belongs to the peptidase S9A family. |
| UniProt Protein Details: | Protein type:EC 3.4.21.26; Protease Chromosomal Location of Human Ortholog: 6q22 Cellular Component: cytoplasm; membrane Molecular Function:protein binding; serine-type peptidase activity |
| UniProt Code: | P48147 |
| NCBI GenInfo Identifier: | 41349456 |
| NCBI Gene ID: | 5550 |
| NCBI Accession: | NP_002717.3 |
| UniProt Secondary Accession: | P48147,Q8N6D4, |
| UniProt Related Accession: | P48147 |
| Molecular Weight: | 80,700 Da |
| NCBI Full Name: | prolyl endopeptidase |
| NCBI Synonym Full Names: | prolyl endopeptidase |
| NCBI Official Symbol: | PREP |
| NCBI Official Synonym Symbols: | PE; PEP |
| NCBI Protein Information: | prolyl endopeptidase |
| UniProt Protein Name: | Prolyl endopeptidase |
| UniProt Synonym Protein Names: | Post-proline cleaving enzyme |
| Protein Family: | Preprocaerulein |
| UniProt Gene Name: | PREP |
| UniProt Entry Name: | PPCE_HUMAN |
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