Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.
Product Name:
Human PPM1G/PP2C-gamma Recombinant Protein (RPES2411)
Product Code:
RPES2411
Size:
20µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Protein Phosphatase 1G, Protein Phosphatase 1C, Protein Phosphatase 2C Isoform Gamma, PP2C-Gamma, Protein Phosphatase Magnesium-Dependent 1 Gamma, PPM1G, PP2CG,PP2CGAMMA
Accession:
O15355
Sequence:
Met 317-Asp 546
Fusion tag:
N-His
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the human PPM1G (O15355) C-terminal fragment (Met 317-Asp 546) was expressed; with a polyhistidine tag at the N-terminus.
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
