Human POP7 Recombinant Protein (RPPB4280)

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SKU:
RPPB4280
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
POP7
Synonyms:
Ribonuclease P protein subunit p20
Synonyms:
RNaseP protein p20
Synonyms:
Ribonucleases P/MRP protein subunit POP7 homolog
Synonyms:
hPOP7
Source:
Escherichia Coli
Uniprot:
O75817
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Description

Product Name:Human POP7 Recombinant Protein
Product Code:RPPB4280
Size:10µg
Species:Human
Target:POP7
Synonyms:Ribonuclease P protein subunit p20, RNaseP protein p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7, POP7, RPP20, 0610037N12Rik, RPP2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:POP7 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 50% glycerol, 2mM DTT and 2mM EDTA.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSEFMAENR EPRGAVEAEL DPVEYTLRKR LPSRLPRRPN DIYVNMKTDF KAQLARCQKL LDGGARGQNA CSEIYIHGLG LAINRAINIA LQLQAGSFGS LQVAANTSTV ELVDELEPET DTREPLTRIR NNSAIHIRVF RVTPK

Processing Of Precursor 7, also known as POP7, is a part of the histone-like Alba family. POP7 is a part of ribonuclease P which is a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. POP7 is also a part of RNase MRP complex, which cleaves pre-rRNA sequences.

POP7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-140 a.a.) and having a molecular mass of 18.3kDa.POP7 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:POP7: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the histone-like Alba family.
UniProt Protein Details:

Protein type:Nucleolus; Ribonuclease; EC 3.1.26.5

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: nucleolar ribonuclease P complex; nucleus

Molecular Function:protein binding; ribonuclease P activity

Biological Process: tRNA processing

UniProt Code:O75817
NCBI GenInfo Identifier:153791431
NCBI Gene ID:10248
NCBI Accession:NP_005828.2
UniProt Secondary Accession:O75817,Q9BV74, A4D2E0,
UniProt Related Accession:O75817
Molecular Weight:42.7 kDa
NCBI Full Name:ribonuclease P protein subunit p20
NCBI Synonym Full Names:processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
NCBI Official Symbol:POP7  
NCBI Official Synonym Symbols:RPP2; RPP20; 0610037N12Rik  
NCBI Protein Information:ribonuclease P protein subunit p20; hPOP7; RNaseP protein p20; ribonucleases P/MRP protein subunit POP7 homolog; processing of precursor 7, ribonuclease P subunit; POP7 (processing of precursor, S. cerevisiae) homolog
UniProt Protein Name:Ribonuclease P protein subunit p20
UniProt Synonym Protein Names:Ribonucleases P/MRP protein subunit POP7 homolog; hPOP7
Protein Family:Ribonuclease P protein
UniProt Gene Name:POP7  
UniProt Entry Name:POP7_HUMAN
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