Human PON3/Paraoxonase 3 Recombinant Protein (RPES4632)
- SKU:
- RPES4632
- Product type:
- Recombinant Protein
- Host species:
- Baculovirus-Insect Cells
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human PON3/Paraoxonase 3 Recombinant Protein
KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
Product Name: | Human PON3/Paraoxonase 3 Recombinant Protein (RPES4632) |
Product Code: | RPES4632 |
Size: | 20µg |
Species: | Human |
Expressed Host: | Baculovirus-Insect Cells |
Synonyms: | PON3 |
Accession: | Q15166-1 |
Sequence: | Met 1-Leu 354 |
Fusion tag: | N-His |
Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
Protein Construction: | A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus. |
Purity: | > 85 % as determined by reducing SDS-PAGE. |
Mol Mass: | 42 kDa |
AP Mol Mass: | 45 kDa |
Formulation: | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 1mM CaCL2, 10% gly, 0.1% DDM |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |