Human PLAC8 Recombinant Protein (RPPB4257)

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SKU:
RPPB4257
Product type:
Recombinant Protein
Size:
25ug
Species:
Human
Target:
PLAC8
Synonyms:
 Placenta-Specific 8
Synonyms:
C15
Synonyms:
Onzin
Synonyms:
Placenta-Specific Gene 8 Protein
Source:
Escherichia Coli
Uniprot:
Q9NZF1
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Description

Product Name:Human PLAC8 Recombinant Protein
Product Code:RPPB4257
Size:25µg
Species:Human
Target:PLAC8
Synonyms: Placenta-Specific 8, C15, Onzin, Placenta-Specific Gene 8 Protein, Protein C15.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:PLAC8 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0),0.4M urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMQAQAPV VVVTQPGVGP GPAPQNSNWQ TGMCDCFSDC GVCLCGTFCF PCLGCQVAAD MNECCLCGTS VAMRTLYRTR YGIPGSICDD YMATLCCPHC TLCQIKRDIN RRRAMRTF

Placenta-Specific 8 (PLAC8) is a member of the cornifelin family. The PLAC8 protein is expressed at high levels in the plasmacytoid dendritic cells, spleen, lymph nodes, peripheral blood leukocytes, and bone marrow.

PLAC8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 138 amino acids (1-115 a.a) and having a molecular mass of 14.9kDa.PLAC8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:PLAC8: Belongs to the cornifelin family.Chromosomal Location of Human Ortholog: 4q21.22Molecular Function: chromatin bindingBiological Process: brown fat cell differentiation; defense response to bacterium; negative regulation of apoptosis; negative regulation of multicellular organism growth; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to cold
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9NZF1
NCBI GenInfo Identifier:195222740
NCBI Gene ID:51316
NCBI Accession:NP_001124188.1
UniProt Secondary Accession:Q9NZF1,C1K3N2
UniProt Related Accession:Q9NZF1
Molecular Weight:
NCBI Full Name:placenta-specific gene 8 protein
NCBI Synonym Full Names:placenta specific 8
NCBI Official Symbol:PLAC8  
NCBI Official Synonym Symbols:C15; DGIC; onzin; PNAS-144  
NCBI Protein Information:placenta-specific gene 8 protein
UniProt Protein Name:Placenta-specific gene 8 protein
UniProt Synonym Protein Names:Protein C15
Protein Family:PLAC8-like protein
UniProt Gene Name:PLAC8  
UniProt Entry Name:PLAC8_HUMAN
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