Human PFK1/PFKM Recombinant Protein (RPES2459)

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SKU:
RPES2459
Product type:
Recombinant Protein
Host species:
Baculovirus-Insect Cells
Reactivity:
Human
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Description

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Human PFK1/PFKM Recombinant Protein

PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.

Product Name:Human PFK1/PFKM Recombinant Protein (RPES2459)
Product Code:RPES2459
Size:50µg
Species:Human
Expressed Host:Baculovirus-Insect Cells
Synonyms:6-phosphofructokinase, muscle type,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,PFKM,PFKX,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PPP1R122
Accession:P08237-1
Sequence:Thr 2-Val 780
Fusion tag:N-His & GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human PFKM (P08237-1) (Thr2-Val780) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:112.9 kDa
AP Mol Mass:113 kDa
Formulation:Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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