Human PDRG1 Recombinant Protein (RPPB4217)
- SKU:
- RPPB4217
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- PDRG1
- Synonyms:
- p53 and DNA damage-regulated protein 1
- PDRG1
- C20orf126
- PDRG
- Source:
- Escherichia Coli
- Uniprot:
- Q9NUG6
Description
| Product Name: | Human PDRG1 Recombinant Protein |
| Product Code: | RPPB4217 |
| Size: | 20µg |
| Species: | Human |
| Target: | PDRG1 |
| Synonyms: | p53 and DNA damage-regulated protein 1, PDRG1, C20orf126, PDRG. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PDRG1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 5mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG |
PDRG1 is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit beta family. PDRG1 is expressed primarily in normal testicular tissue, it is functionally induced by ultraviolet light and is thought to have a role in chaperone-mediated protein folding, possibly having a role in cellular degradation. PDRG1 is linked to Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
PDRG1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 153 amino acids (1-133 a.a.) and having a molecular mass of 17.6kDa. The PDRG1 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PDRG1: May play a role in chaperone-mediated protein folding (Potential). Belongs to the prefoldin subunit beta family.Chromosomal Location of Human Ortholog: 20q11.21 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NUG6 |
| NCBI GenInfo Identifier: | 24211602 |
| NCBI Gene ID: | 81572 |
| NCBI Accession: | Q9NUG6.2 |
| UniProt Secondary Accession: | Q9NUG6,Q96GP3, Q9BUW8, B2R511 |
| UniProt Related Accession: | Q9NUG6 |
| Molecular Weight: | 15,511 Da |
| NCBI Full Name: | p53 and DNA damage-regulated protein 1 |
| NCBI Synonym Full Names: | p53 and DNA damage regulated 1 |
| NCBI Official Symbol: | PDRG1 |
| NCBI Official Synonym Symbols: | PDRG; C20orf126 |
| NCBI Protein Information: | p53 and DNA damage-regulated protein 1 |
| UniProt Protein Name: | p53 and DNA damage-regulated protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | p53 and DNA damage-regulated protein |
| UniProt Gene Name: | PDRG1 |
| UniProt Entry Name: | PDRG1_HUMAN |
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