Human PBLD Recombinant Protein (RPPB4192)

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SKU:
RPPB4192
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
PBLD
Synonyms:
Phenazine biosynthesis-like domain-containing protein
Synonyms:
MAWD-binding protein
Synonyms:
Unknown protein 32 from 2D-page of liver tissue
Synonyms:
PBLD
Source:
Escherichia Coli
Uniprot:
P30039
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Description

Product Name:Human PBLD Recombinant Protein
Product Code:RPPB4192
Size:20µg
Species:Human
Target:PBLD
Synonyms:Phenazine biosynthesis-like domain-containing protein, MAWD-binding protein, Unknown protein 32 from 2D-page of liver tissue, PBLD, MAWBP, MAWDBP, FLJ14767, FLJ35507.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The PBLD solution (1 mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MKLPIFIADA FTARAFRGNP AAVCLLENEL DEDMHQKIAR EMNLSETAFI RKLHPTDNFA QSSCFGLRWF TPASEVPLCG HATLASAAVL FHKIKNMNST LTFVTLSGEL RARRAEDGIV LDLPLYPAHP QDFHEVEDLI KTAIGNTLVQ DICYSPDTQK LLVRLSDVYN RSFLENLKVN TENLLQVENT GKVKGLILTL KGEPGGQTQA FDFYSRYFAP WVGVAEDPVT GSAHAVLSSY WSQHLGKKEM HAFQCSHRGG ELGISLRPDG RVDIRGGAAV VLEGTLTA

PBLD is member of the phenazine biosynthesis-like protein (PhzF) family. PBLD which is expressed in most tissues is the only representative of the PhzF family in the human genome. PBLD participates in the MAPK signaling pathway. PBLD is involved in multiple basic cellular functions, its expression is elevated in several disease processes, including folate deficiency and hypotension.

PBLD Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 308 amino acids (1-288 a.a.) and having a molecular mass of 33.9kDa. The PBLD is purified by proprietary chromatographic techniques.

UniProt Protein Function:PBLD: Belongs to the PhzF family.Protein type: Isomerase; EC 5.1.-.-Chromosomal Location of Human Ortholog: 10q21.3Cellular Component: cytoplasmMolecular Function: protein bindingBiological Process: maintenance of gastrointestinal epithelium; negative regulation of epithelial cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway
UniProt Protein Details:
NCBI Summary:
UniProt Code:P30039
NCBI GenInfo Identifier:17380331
NCBI Gene ID:64081
NCBI Accession:P30039.2
UniProt Secondary Accession:P30039,Q9HCC2, A8MZJ3, C9JIM0
UniProt Related Accession:P30039
Molecular Weight:31,409 Da
NCBI Full Name:Phenazine biosynthesis-like domain-containing protein
NCBI Synonym Full Names:phenazine biosynthesis like protein domain containing
NCBI Official Symbol:PBLD  
NCBI Official Synonym Symbols:MAWBP; MAWDBP; HEL-S-306  
NCBI Protein Information:phenazine biosynthesis-like domain-containing protein
UniProt Protein Name:Phenazine biosynthesis-like domain-containing protein
UniProt Synonym Protein Names:MAWD-binding protein; MAWDBP; Unknown protein 32 from 2D-page of liver tissue
Protein Family:Phenazine biosynthesis-like domain-containing protein
UniProt Gene Name:PBLD  
UniProt Entry Name:PBLD_HUMAN
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