Human P4HB Recombinant Protein (RPES3471)

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SKU:
RPES3471
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human P4HB Recombinant Protein

Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.

Product Name:Human P4HB Recombinant Protein (RPES3471)
Product Code:RPES3471
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB,Protein Disulfide-Isomerase, PDI, Cellular Thyroid Hormone-Binding Protein, Prolyl 4-Hydroxylase Subunit Beta, p55
Accession:NP_000909.2
Sequence:Asp18-Lys505
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Prolyl 4-Hydroxylase Subunit Beta is produced by our E.coli expression system and the target gene encoding Asp18-Lys505 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:55.9 kDa
AP Mol Mass:68 kDa
Formulation:Supplied as a 0.2 µm filtered solution of PBS, pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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