Human ORAOV1 Recombinant Protein (RPPB4164)

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SKU:
RPPB4164
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
ORAOV1
Synonyms:
Oral cancer-overexpressed protein 1
Synonyms:
Tumor-amplified and overexpressed sequence 1
Synonyms:
ORAOV1
Synonyms:
TAOS1
Source:
Escherichia Coli
Uniprot:
Q8WV07
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Description

Product Name:Human ORAOV1 Recombinant Protein
Product Code:RPPB4164
Size:10µg
Species:Human
Target:ORAOV1
Synonyms:Oral cancer-overexpressed protein 1, Tumor-amplified and overexpressed sequence 1, ORAOV1, TAOS1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ORAOV1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMAGSQD IFDAIVMADE RFHGEGYREG YEEGSSLGVM EGRQHGTLHG AKIGSEIGCY QGFAFAWKCL LHSCTTEKDS RKMKVLESLI GMIQKFPYDD PTYDKLHEDL DKIRGKFKQF CSLLNVQPDF KISAEGSGLS F

Oral cancer-overexpressed protein 1 (ORAOV1) is a candidate oncogene in the 11q13 chromosomal region. Functional analyses showed that ORAOV1 was involved in the regulation of HeLa cell growth via its effect on cell cycle and apoptosis. ORAOV1 is widely expressed; it has a high expression in the placenta, kidney and skeletal muscle. ORAOV1 is amplified and overexpressed in oral cancer cells.

ORAOV1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 161 amino acids (1-137 a.a) and having a molecular mass of 17.9kDa.ORAOV1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ORAOV1: Belongs to the ORAOV1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 11q13.3Biological Process: ribosomal large subunit biogenesis and assembly
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WV07
NCBI GenInfo Identifier:85701377
NCBI Gene ID:220064
NCBI Accession:Q8WV07.2
UniProt Secondary Accession:Q8WV07,Q8NFK0, B2R4R2
UniProt Related Accession:Q8WV07
Molecular Weight:15,354 Da
NCBI Full Name:Oral cancer-overexpressed protein 1
NCBI Synonym Full Names:oral cancer overexpressed 1
NCBI Official Symbol:ORAOV1  
NCBI Official Synonym Symbols:TAOS1  
NCBI Protein Information:oral cancer-overexpressed protein 1
UniProt Protein Name:Oral cancer-overexpressed protein 1
UniProt Synonym Protein Names:Tumor-amplified and overexpressed sequence 1
Protein Family:Oral cancer-overexpressed protein
UniProt Gene Name:ORAOV1  
UniProt Entry Name:ORAV1_HUMAN
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