Human OLFM1 Recombinant Protein (RPPB4153)
- SKU:
- RPPB4153
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- OLFM1
- Synonyms:
- olfactomedin 1
- NOE1
- NOELIN1
- OlfA
- Source:
- Escherichia Coli
- Uniprot:
- Q99784
Description
| Product Name: | Human OLFM1 Recombinant Protein |
| Product Code: | RPPB4153 |
| Size: | 10µg |
| Species: | Human |
| Target: | OLFM1 |
| Synonyms: | olfactomedin 1, NOE1, NOELIN1, OlfA, Noelin, Neuronal olfactomedin-related ER localized protein. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | OLFM1 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 7.5), 0.2M NaCl, 50% glycerol and 5mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLPTNPEE SWQVYSSAQD SEGRCICTVV APQQTMCSRD ARTKQLRQLL EKVQNMSQSI EVLDRRTQRD LQYVEKMENQ MKGLESKFKQ VEESHKQHLA RQFKG |
Olfactomedin 1 (OLFM1), also known as noelin, shares expansive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. OLFM1 plays a vital role in regulating the production of neural crest cells by the neural tube.
OLFM1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 125 amino acids (34-135 a.a.) and having a molecular mass of 14.3kDa.OLFM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | OLFM1: Seems to play an important role in regulating the production of neural crest cells by the neural tube. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Cell adhesion Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: extracellular space; synapse; cell junction Molecular Function:protein binding; beta-amyloid binding Biological Process: nervous system development; protein oligomerization |
| NCBI Summary: | This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99784 |
| NCBI GenInfo Identifier: | 206729935 |
| NCBI Gene ID: | 10439 |
| NCBI Accession: | Q99784.4 |
| UniProt Secondary Accession: | Q99784,Q53XZ8, Q6IMJ4, Q6IMJ5, Q8N8R0, Q969S7, Q99452 |
| UniProt Related Accession: | Q99784 |
| Molecular Weight: | 485 |
| NCBI Full Name: | Noelin |
| NCBI Synonym Full Names: | olfactomedin 1 |
| NCBI Official Symbol: | OLFM1 |
| NCBI Official Synonym Symbols: | AMY; NOE1; OlfA; NOELIN1 |
| NCBI Protein Information: | noelin; pancortin 1; olfactomedin-1; neuroblastoma protein; olfactomedin related ER localized protein; neuronal olfactomedin-related ER localized protein |
| UniProt Protein Name: | Noelin |
| UniProt Synonym Protein Names: | Neuronal olfactomedin-related ER localized protein; Olfactomedin-1 |
| Protein Family: | Noelin |
| UniProt Gene Name: | OLFM1 |
| UniProt Entry Name: | NOE1_HUMAN |
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