Human OBFC1/STN1 Recombinant Protein (RPES0843)

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SKU:
RPES0843
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human OBFC1/STN1 Recombinant Protein

CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

Product Name:Human OBFC1/STN1 Recombinant Protein (RPES0843)
Product Code:RPES0843
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1
Accession:Q9H668
Sequence:Met 1-Phe368
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Oligosaccharide-Binding Fold-Containing Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Phe368 is expressed with a 6His tag at the N-terminus.
Purity:> 85 % as determined by reducing SDS-PAGE.
Mol Mass:44.2 kDa
AP Mol Mass:44 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 1mM DTT, pH 8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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