Human NUBP2 Recombinant Protein (RPPB4134)
- SKU:
- RPPB4134
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- NUBP2
- Synonyms:
- Nucleotide Binding Protein 2
- Nucleotide Binding Protein 2 (MinD Homolog
- E Coli)
- NBP 2
- Source:
- Escherichia Coli
- Uniprot:
- Q9Y5Y2
Description
| Product Name: | Human NUBP2 Recombinant Protein |
| Product Code: | RPPB4134 |
| Size: | 10µg |
| Species: | Human |
| Target: | NUBP2 |
| Synonyms: | Nucleotide Binding Protein 2, Nucleotide Binding Protein 2 (MinD Homolog, E. Coli), NBP 2,CFD1, C447E6.1 (Nucleotide Binding Protein 1 (E.Coli MinD Like) ), Homolog Of Yeast Cytosolic Fe-S Cluster Deficient 1, Nucleotide Binding Protein 2 (E.Coli MinD Like), Cytosolic Fe-S Cluster Assembly Factor NUBP2, Nucleotide-Binding Protein 2, NUBP1, NUBP2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | NUBP2 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 50% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMEAAAEP GNLAGVRHII LVLSGKGGVG KSTISTELAL ALRHAGKKVG ILDVDLCGPS IPRMLGAQGR AVHQCDRGWA PVFLDREQSI SLMSVGFLLE KPDEAVVWRG PKKNALIKQF VSDVAWGELD YLVVDTPPGT SDEHMATIEA LRPYQPLGAL VVTTPQAVSV GDVRRELTFC RKTGLRVMGI VENMSGFTCP HCTECTSVFS RGGGEELAQL AGVPFLGSVP LDPALMRTLE EGHDFIQEFP GSPAFAALTS IAQKILDATP ACLP |
Nucleotide Binding Protein 2, also known as NUBP2 is an adenosinetriphosphate (ATP) as well as metal-binding protein which is essential for theassembly of cyotosolic iron-sulfurproteins. NUBP2 performs in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Moreover,alternative splicing results in multiple transcript variants have been foundfor NUBP2.
NUBP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 294 amino acids (1-271 a.a) and having a molecular mass of 31.2kDa.NUBP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NUBP2: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins. Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: cytoplasm; spindle pole centrosome; nucleus Molecular Function:protein binding; metal ion binding; 4 iron, 4 sulfur cluster binding; nucleotide binding; ATP binding Biological Process: iron-sulfur cluster assembly |
| NCBI Summary: | This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
| UniProt Code: | Q9Y5Y2 |
| NCBI GenInfo Identifier: | 548962168 |
| NCBI Gene ID: | 10101 |
| NCBI Accession: | NP_001271431.1 |
| UniProt Secondary Accession: | Q9Y5Y2,Q9NWB2, D3DU80, |
| UniProt Related Accession: | Q9Y5Y2 |
| Molecular Weight: | 28,825 Da |
| NCBI Full Name: | cytosolic Fe-S cluster assembly factor NUBP2 isoform 3 |
| NCBI Synonym Full Names: | nucleotide binding protein 2 |
| NCBI Official Symbol: | NUBP2 |
| NCBI Official Synonym Symbols: | CFD1; NBP 2; NUBP1 |
| NCBI Protein Information: | cytosolic Fe-S cluster assembly factor NUBP2; homolog of yeast cytosolic Fe-S cluster deficient 1; nucleotide binding protein 2 (MinD homolog, E. coli); C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) ) |
| UniProt Protein Name: | Cytosolic Fe-S cluster assembly factor NUBP2 |
| UniProt Synonym Protein Names: | Nucleotide-binding protein 2; NBP 2 |
| Protein Family: | Cytosolic Fe-S cluster assembly factor |
| UniProt Gene Name: | NUBP2 |
| UniProt Entry Name: | NUBP2_HUMAN |
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