Human NUBP2 Recombinant Protein (RPPB4134)

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SKU:
RPPB4134
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
NUBP2
Synonyms:
Nucleotide Binding Protein 2
Synonyms:
Nucleotide Binding Protein 2 (MinD Homolog
Synonyms:
E Coli)
Synonyms:
NBP 2
Source:
Escherichia Coli
Uniprot:
Q9Y5Y2
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Description

Product Name:Human NUBP2 Recombinant Protein
Product Code:RPPB4134
Size:10µg
Species:Human
Target:NUBP2
Synonyms:Nucleotide Binding Protein 2, Nucleotide Binding Protein 2 (MinD Homolog, E. Coli), NBP 2,CFD1, C447E6.1 (Nucleotide Binding Protein 1 (E.Coli MinD Like) ), Homolog Of Yeast Cytosolic Fe-S Cluster Deficient 1, Nucleotide Binding Protein 2 (E.Coli MinD Like), Cytosolic Fe-S Cluster Assembly Factor NUBP2, Nucleotide-Binding Protein 2, NUBP1, NUBP2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:NUBP2 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 50% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMEAAAEP GNLAGVRHII LVLSGKGGVG KSTISTELAL ALRHAGKKVG ILDVDLCGPS IPRMLGAQGR AVHQCDRGWA PVFLDREQSI SLMSVGFLLE KPDEAVVWRG PKKNALIKQF VSDVAWGELD YLVVDTPPGT SDEHMATIEA LRPYQPLGAL VVTTPQAVSV GDVRRELTFC RKTGLRVMGI VENMSGFTCP HCTECTSVFS RGGGEELAQL AGVPFLGSVP LDPALMRTLE EGHDFIQEFP GSPAFAALTS IAQKILDATP ACLP

Nucleotide Binding Protein 2, also known as NUBP2 is an adenosinetriphosphate (ATP) as well as metal-binding protein which is essential for theassembly of  cyotosolic iron-sulfurproteins. NUBP2 performs in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Moreover,alternative splicing results in multiple transcript variants have been foundfor NUBP2.

NUBP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 294 amino acids (1-271 a.a) and having a molecular mass of 31.2kDa.NUBP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:NUBP2: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins. Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasm; spindle pole centrosome; nucleus

Molecular Function:protein binding; metal ion binding; 4 iron, 4 sulfur cluster binding; nucleotide binding; ATP binding

Biological Process: iron-sulfur cluster assembly

NCBI Summary:This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
UniProt Code:Q9Y5Y2
NCBI GenInfo Identifier:548962168
NCBI Gene ID:10101
NCBI Accession:NP_001271431.1
UniProt Secondary Accession:Q9Y5Y2,Q9NWB2, D3DU80,
UniProt Related Accession:Q9Y5Y2
Molecular Weight:28,825 Da
NCBI Full Name:cytosolic Fe-S cluster assembly factor NUBP2 isoform 3
NCBI Synonym Full Names:nucleotide binding protein 2
NCBI Official Symbol:NUBP2  
NCBI Official Synonym Symbols:CFD1; NBP 2; NUBP1  
NCBI Protein Information:cytosolic Fe-S cluster assembly factor NUBP2; homolog of yeast cytosolic Fe-S cluster deficient 1; nucleotide binding protein 2 (MinD homolog, E. coli); C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) )
UniProt Protein Name:Cytosolic Fe-S cluster assembly factor NUBP2
UniProt Synonym Protein Names:Nucleotide-binding protein 2; NBP 2
Protein Family:Cytosolic Fe-S cluster assembly factor
UniProt Gene Name:NUBP2  
UniProt Entry Name:NUBP2_HUMAN
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