Human NOP16 Recombinant Protein (RPPB4117)
- SKU:
- RPPB4117
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- NOP16
- Synonyms:
- Nucleolar protein 16
- HBV pre-S2 trans-regulated protein 3
- NOP16
- CGI-117
- Source:
- Escherichia Coli
- Uniprot:
- Q9Y3C1
Frequently bought together:
Description
| Product Name: | Human NOP16 Recombinant Protein |
| Product Code: | RPPB4117 |
| Size: | 10µg |
| Species: | Human |
| Target: | NOP16 |
| Synonyms: | Nucleolar protein 16, HBV pre-S2 trans-regulated protein 3, NOP16, CGI-117, HSPC111, HSPC185. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | NOP16 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM EDTA and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMPKAKGK TRRQKFGYSV NRKRLNRNAR RKAAPRIECS HIRHAWDHAK SVRQNLAEMG LAVDPNRAVP LRKRKVKAME VDIEERPKEL VRKPYVLNDL EAEASLPEKK GNTLSRDLID YVRYMVENHG EDYKAMARDE KNYYQDTPKQ IRSKINVYKR FYPAEWQDFL DSLQKRKMEV E |
The NOP16 protein is transcriptionally regulated by c-Myc and upregulated in breast cancer. NOP16 overexpression is linked with poor patient survival.
NOP16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-178 a.a) and having a molecular mass of 23.6kDa.NOP16 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| NCBI Summary: | This gene encodes a protein that is localized to the nucleolus. Expression of this gene is induced by estrogens and Myc protein and is a marker of poor patient survival in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q9Y3C1 |
| NCBI GenInfo Identifier: | 115311631 |
| NCBI Gene ID: | 51491 |
| NCBI Accession: | Q9Y3C1.2 |
| UniProt Secondary Accession: | Q9Y3C1,Q05D05, Q6IAI6, Q6PIM0, Q8IXL5, B4DV13, D6RGD3 |
| UniProt Related Accession: | Q9Y3C1 |
| Molecular Weight: | 26,561 Da |
| NCBI Full Name: | Nucleolar protein 16 |
| NCBI Synonym Full Names: | NOP16 nucleolar protein |
| NCBI Official Symbol: | NOP16 |
| NCBI Official Synonym Symbols: | HSPC111; HSPC185 |
| NCBI Protein Information: | nucleolar protein 16 |
| UniProt Protein Name: | Nucleolar protein 16 |
| UniProt Synonym Protein Names: | HBV pre-S2 trans-regulated protein 3 |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP16 |
| UniProt Entry Name: | NOP16_HUMAN |
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