Human NOP16 Recombinant Protein (RPPB4117)

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SKU:
RPPB4117
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
NOP16
Synonyms:
Nucleolar protein 16
Synonyms:
HBV pre-S2 trans-regulated protein 3
Synonyms:
NOP16
Synonyms:
CGI-117
Source:
Escherichia Coli
Uniprot:
Q9Y3C1
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Description

Product Name:Human NOP16 Recombinant Protein
Product Code:RPPB4117
Size:10µg
Species:Human
Target:NOP16
Synonyms:Nucleolar protein 16, HBV pre-S2 trans-regulated protein 3, NOP16, CGI-117, HSPC111, HSPC185.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:NOP16 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM EDTA and 2mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMPKAKGK TRRQKFGYSV NRKRLNRNAR RKAAPRIECS HIRHAWDHAK SVRQNLAEMG LAVDPNRAVP LRKRKVKAME VDIEERPKEL VRKPYVLNDL EAEASLPEKK GNTLSRDLID YVRYMVENHG EDYKAMARDE KNYYQDTPKQ IRSKINVYKR FYPAEWQDFL DSLQKRKMEV E

The NOP16 protein is transcriptionally regulated by c-Myc and upregulated in breast cancer. NOP16 overexpression is linked with poor patient survival.

NOP16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-178 a.a) and having a molecular mass of 23.6kDa.NOP16 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

NCBI Summary:This gene encodes a protein that is localized to the nucleolus. Expression of this gene is induced by estrogens and Myc protein and is a marker of poor patient survival in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Code:Q9Y3C1
NCBI GenInfo Identifier:115311631
NCBI Gene ID:51491
NCBI Accession:Q9Y3C1.2
UniProt Secondary Accession:Q9Y3C1,Q05D05, Q6IAI6, Q6PIM0, Q8IXL5, B4DV13, D6RGD3
UniProt Related Accession:Q9Y3C1
Molecular Weight:26,561 Da
NCBI Full Name:Nucleolar protein 16
NCBI Synonym Full Names:NOP16 nucleolar protein
NCBI Official Symbol:NOP16  
NCBI Official Synonym Symbols:HSPC111; HSPC185  
NCBI Protein Information:nucleolar protein 16
UniProt Protein Name:Nucleolar protein 16
UniProt Synonym Protein Names:HBV pre-S2 trans-regulated protein 3
Protein Family:Nucleolar protein
UniProt Gene Name:NOP16  
UniProt Entry Name:NOP16_HUMAN
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