Human NHLH2 Recombinant Protein (RPPB4094)

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SKU:
RPPB4094
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
NHLH2
Synonyms:
nescient helix loop helix 2
Synonyms:
bHLHa34
Synonyms:
HEN2
Synonyms:
NSCL2
Source:
Escherichia Coli
Uniprot:
Q02577
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Description

Product Name:Human NHLH2 Recombinant Protein
Product Code:RPPB4094
Size:10µg
Species:Human
Target:NHLH2
Synonyms:nescient helix loop helix 2, bHLHa34, HEN2, NSCL2, Class A basic helix-loop-helix protein 34, NHLH2, KIAA0490.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:NHLH2 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.2M NaCl, 50% glycerol and 5mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMMLSPDQ AADSDHPSSA HSDPESLGGT DTKVLGSVSD LEPVEEAEGD GKGGSRAALY PHPQQLSREE KRRRRRATAK YRSAHATRER IRVEAFNLAF AELRKLLPTL PPDKKLSKIE ILRLAICYIS YLNHVLDV

Nescient Helix Loop Helix 2 (NHLH2) belongs to the basic helix-loop-helix (bHLH) transcription factor family. NHLH2 is expressed in developing and adult neuroendocrine tissues for example the pituitary and hypothalamus. NHLH2 can act as a DNA-binding protein and may be involved in the control of cell-type determination, probably in the developing nervous system.

NHLH2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (1-135 a.a.) and having a molecular mass of 17.4kDa.NHLH2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:NHLH2: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.Chromosomal Location of Human Ortholog: 1p12-p11Cellular Component: nucleus; transcription factor complexMolecular Function: protein bindingBiological Process: central nervous system development; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q02577
NCBI GenInfo Identifier:399887
NCBI Gene ID:4808
NCBI Accession:Q02577.1
UniProt Secondary Accession:Q02577,Q5T1P6
UniProt Related Accession:Q02577
Molecular Weight:15,018 Da
NCBI Full Name:Helix-loop-helix protein 2
NCBI Synonym Full Names:nescient helix-loop-helix 2
NCBI Official Symbol:NHLH2  
NCBI Official Synonym Symbols:HEN2; NSCL2; bHLHa34  
NCBI Protein Information:helix-loop-helix protein 2
UniProt Protein Name:Helix-loop-helix protein 2
UniProt Synonym Protein Names:Class A basic helix-loop-helix protein 34; bHLHa34; Nescient helix loop helix 2; NSCL-2
Protein Family:Helix-loop-helix protein
UniProt Gene Name:NHLH2  
UniProt Entry Name:HEN2_HUMAN
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