Human Neurotrophin-3/NTF3 Recombinant Protein (RPES0375)

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SKU:
RPES0375
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Neurotrophin-3/NTF3 Recombinant Protein

Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

Product Name:Human Neurotrophin-3/NTF3 Recombinant Protein (RPES0375)
Product Code:RPES0375
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
Accession:P20783
Sequence:Tyr139-Thr 257
Fusion tag:
Activity:Immobilized Human NT-3 at 10ug/ml(100 ?l/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:13.6 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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