Human NCF2/P67phox Recombinant Protein (RPES3502)
- SKU:
- RPES3502
- Product type:
- Recombinant Protein
- Host species:
- Baculovirus-Insect Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human NCF2/P67phox Recombinant Protein
NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
| Product Name: | Human NCF2/P67phox Recombinant Protein (RPES3502) |
| Product Code: | RPES3502 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | NCF-2,NOXA2,P67-PHOX,P67PHOX |
| Accession: | AAH01606.1 |
| Sequence: | Met 1-Val526 |
| Fusion tag: | N-His & GST |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 87.6 kDa |
| AP Mol Mass: | 80-90 kDa |
| Formulation: | Lyophilized from sterile 20mM Tris, 500mM Nacl, 10% glycerol, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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