PE/Cyanine7 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0684)

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SKU:
AGEL0684
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The Human/Mouse/Rat CD47 Monoclonal Antibody (PE/Cyanine7 Conjugated, MIAP410) is a versatile tool for researchers studying CD47, a crucial cell surface protein involved in various cellular processes, including immune modulation and cell signaling. This antibody, conjugated with PE/Cyanine7, offers precise detection and analysis of CD47 expression in human, mouse, and rat samples, making it suitable for a wide range of research applications.CD47, also known as integrin-associated protein, is known for its role in immune regulation and self-recognition. It plays a key role in modulating phagocytosis, cell adhesion, and apoptosis, making it a target of interest in studies related to immunity, cancer biology, and inflammation. By specifically targeting CD47, researchers can explore its functions in different cell types and gain insights into its implications in health and disease.

This monoclonal antibody, MIAP410, provides researchers with a reliable tool for investigating the molecular mechanisms involving CD47, allowing for detailed analyses of its expression levels and localization. With its PE/Cyanine7 conjugation, this antibody offers enhanced fluorescence signal intensity and stability, facilitating accurate flow cytometry and imaging experiments for in-depth research studies.By utilizing the Human/Mouse/Rat CD47 Monoclonal Antibody (PE/Cyanine7 Conjugated, MIAP410), researchers can advance their understanding of CD47 biology and its contributions to diverse physiological and pathological processes, laying the groundwork for potential therapeutic interventions and diagnostic strategies in various fields of biomedical research.

Product Title:PE/Cyanine7 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0684
Size:25µg, 100µg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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