Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0107)

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SKU:
AGEL0107
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Mouse
Isotype:
IgG1
Clone:
MIAP410
Conjugation:
Unconjugated
Applications:
FC
Frequently bought together:

Description

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Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (MIAP410) from Assay Genie (Product Code: AGEL0107) is a cutting-edge research tool designed for the study of CD47, a protein known to have diverse roles in cell regulation and immune responses in humans, mice, and rats. This monoclonal antibody is specifically engineered to target CD47 and has been rigorously validated for its efficacy in various research applications.CD47, a widely studied cell surface marker, is recognized for its involvement in immune evasion, cell signaling, and regulation of cell death processes. By using the CD47 Monoclonal Antibody (MIAP410), researchers can accurately detect and analyze the expression of CD47 in different cell types and experimental settings.

This antibody is versatile and suitable for techniques such as Western blotting, immunofluorescence, and flow cytometry, making it an indispensable tool for immunology and cancer researchers.Given the critical roles of CD47 in various physiological and pathological processes, such as cancer progression and immune modulation, the CD47 Monoclonal Antibody (MIAP410) holds immense promise for advancing our understanding of these complex mechanisms. By investigating the functions of CD47 with this high-quality antibody, researchers can unravel new insights into the interplay between immune responses and disease development, paving the way for innovative therapeutic strategies in oncology and immunotherapy.

Product Title:Purified Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0107
Size:25µg, 100µg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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