FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0669)

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SKU:
AGEL0669
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
MIAP410
Conjugation:
FITC
Frequently bought together:

Description

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FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (FITC Conjugated, MIAP410) is a versatile tool for researchers studying CD47, a widely studied cell surface protein involved in immune regulation and signal transduction. This antibody, conjugated with FITC for fluorescence detection, is compatible with human, mouse, and rat samples, providing flexibility for various experimental models.CD47, also known as integrin-associated protein, is a key player in immune recognition and cell signaling pathways. By binding specifically to CD47, this monoclonal antibody enables precise detection and visualization of the protein in a range of cell types and tissues.

Its application in flow cytometry and fluorescence microscopy makes it invaluable for investigations in immunology, oncology, and stem cell research.Given the diverse functions of CD47 in immune evasion, cell migration, and self-recognition, this antibody is essential for probing its role in diseases such as cancer, cardiovascular disorders, and immune-mediated conditions. Researchers seeking to unravel the intricate mechanisms of CD47 signaling and its implications for therapeutic interventions will find this FITC-conjugated monoclonal antibody an indispensable asset in their studies.

Product Title:FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0669
Size:20 Tests, 100 Tests, 200 Tests
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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