GenieFluor 488 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0677)

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SKU:
AGEL0677
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
MIAP410
Conjugation:
AF 488
Frequently bought together:

Description

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GenieFluor 488 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (AF488 Conjugated, MIAP410) is a cutting-edge tool for researchers investigating the CD47 protein across multiple species including human, mouse, and rat. This monoclonal antibody, conjugated with AF488 for fluorescent detection, is specifically designed for use in flow cytometry and immunofluorescence applications, enabling precise and efficient analysis of CD47 expression and distribution in various biological samples.CD47, a widely studied cell surface protein, plays a pivotal role in immune regulation and cell signaling pathways. It is known for its diverse functions, including the modulation of phagocytosis and regulation of immune response activation.

The AF488-conjugated CD47 Monoclonal Antibody (MIAP410) offers researchers a reliable tool for investigating the role of CD47 in various physiological and pathological processes, such as cancer progression, immune evasion, and tissue homeostasis.With its high specificity and versatility in detecting CD47 in different species, this monoclonal antibody is a valuable asset for studies in immunology, oncology, and molecular biology. By providing insights into the complex functions of CD47, researchers can uncover novel therapeutic targets and develop innovative strategies for combating diseases associated with dysregulated immune responses.

Product Title:GenieFluor 488 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0677
Size:20 Tests, 100 Tests, 200 Tests
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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