Human/Mouse FGF-8b/FGF8B Recombinant Protein (RPES0191)

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SKU:
RPES0191
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human/Mouse
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Human/Mouse FGF-8b/FGF8B Recombinant Protein

Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.

Product Name:Human/Mouse FGF-8b/FGF8B Recombinant Protein (RPES0191)
Product Code:RPES0191
Size:10µg
Species:Human/Mouse
Expressed Host:E.coli
Synonyms:Fibroblast growth factor 8,Androgen-induced growth factor,Heparin-binding growth factor 8,AIGF,HBGF-8,FGF-8B
Accession:P55075-3/P37237-2
Sequence:Gln23-Arg215
Activity:Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 10-60 ng/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human/Mouse Fibroblast growth factor 8B is produced by our E.coli expression system and the target gene encoding Gln23-Arg215 is expressed.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:22.5 kDa
AP Mol Mass:21 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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