Human MOG Recombinant Protein (RPES4946)

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SKU:
RPES4946
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human MOG Recombinant Protein

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals;namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.

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