Human MOBKL3 Recombinant Protein (RPPB3986)

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SKU:
RPPB3986
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
MOBKL3
Synonyms:
Mps one binder kinase activator-like 3
Synonyms:
2C4D
Synonyms:
Class II mMOB1
Synonyms:
Mob1 homolog 3
Source:
Escherichia Coli
Uniprot:
Q9Y3A3
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Description

Product Name:Human MOBKL3 Recombinant Protein
Product Code:RPPB3986
Size:10µg
Species:Human
Target:MOBKL3
Synonyms:Mps one binder kinase activator-like 3, 2C4D, Class II mMOB1, Mob1 homolog 3, Mob3, Preimplantation protein 3, MOBKL3, MOB3, PREI3, MOB1, PREI3, CGI-95, MGC12264.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The MOBKL3 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 5mM DTT, 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MVMAEGTAVL RRNRPGTKAQ DFYNWPDESF DEMDSTLAVQ QYIQQNIRAD CSNIDKILEP PEGQDEGVWK YEHLRQFCLE LNGLAVKLQS ECHPDTCTQM TATEQWIFLC AAHKTPKECP AIDYTRHTLD GAACLLNSNK YFPSRVSIKE SSVAKLGSVC RRIYRIFSHA YFHHRQIFDE YENETFLCHR FTKFVMKYNL MSKDNLIVPI LEEEVQNSVS GESEA

Mps one binder kinase activator-like 3 (MOBKL3) is a member of the MOB1/Phocein family and is phosphorylated on serine residues. MOBKL3 is usually linked with membranes but can be present in the cytosol, where it behaves as a protein complex. MOBKL3 is the major partner of the striatin family members, which are scaffolding proteins involved in signaling and trafficking.

MOBKL3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-225 a.a.) and having a molecular mass of 28.1kDa. The MOBKL3 is purified by proprietary chromatographic techniques.

UniProt Protein Function:PREI3: May play a role in membrane trafficking, specifically in membrane budding reactions. Belongs to the MOB1/phocein family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Activator; Protein kinase, regulatory subunit; Membrane protein, peripheral

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: cytoplasm; Golgi apparatus

Molecular Function:protein binding

NCBI Summary:This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]
UniProt Code:Q9Y3A3
NCBI GenInfo Identifier:56749365
NCBI Gene ID:25843
NCBI Accession:Q9Y3A3.1
UniProt Secondary Accession:Q9Y3A3,Q53SE0, Q7Z4Y6, Q9H2P3, Q9H5J1, Q9Y4T8, B4DML0
UniProt Related Accession:Q9Y3A3
Molecular Weight:23,513 Da
NCBI Full Name:MOB-like protein phocein
NCBI Synonym Full Names:MOB family member 4, phocein
NCBI Official Symbol:MOB4  
NCBI Official Synonym Symbols:2C4D; MOB1; MOB3; PHOCN; PREI3; CGI-95; MOBKL3  
NCBI Protein Information:MOB-like protein phocein
UniProt Protein Name:MOB-like protein phocein
UniProt Synonym Protein Names:2C4D; Class II mMOB1; Mob1 homolog 3; Mob3; Mps one binder kinase activator-like 3; Preimplantation protein 3
Protein Family:MOB kinase activator
UniProt Gene Name:MOB4  
UniProt Entry Name:PHOCN_HUMAN
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