Human MOBKL3 Recombinant Protein (RPPB3986)
- SKU:
- RPPB3986
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- MOBKL3
- Synonyms:
- Mps one binder kinase activator-like 3
- 2C4D
- Class II mMOB1
- Mob1 homolog 3
- Source:
- Escherichia Coli
- Uniprot:
- Q9Y3A3
Description
| Product Name: | Human MOBKL3 Recombinant Protein |
| Product Code: | RPPB3986 |
| Size: | 10µg |
| Species: | Human |
| Target: | MOBKL3 |
| Synonyms: | Mps one binder kinase activator-like 3, 2C4D, Class II mMOB1, Mob1 homolog 3, Mob3, Preimplantation protein 3, MOBKL3, MOB3, PREI3, MOB1, PREI3, CGI-95, MGC12264. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The MOBKL3 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 5mM DTT, 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MVMAEGTAVL RRNRPGTKAQ DFYNWPDESF DEMDSTLAVQ QYIQQNIRAD CSNIDKILEP PEGQDEGVWK YEHLRQFCLE LNGLAVKLQS ECHPDTCTQM TATEQWIFLC AAHKTPKECP AIDYTRHTLD GAACLLNSNK YFPSRVSIKE SSVAKLGSVC RRIYRIFSHA YFHHRQIFDE YENETFLCHR FTKFVMKYNL MSKDNLIVPI LEEEVQNSVS GESEA |
Mps one binder kinase activator-like 3 (MOBKL3) is a member of the MOB1/Phocein family and is phosphorylated on serine residues. MOBKL3 is usually linked with membranes but can be present in the cytosol, where it behaves as a protein complex. MOBKL3 is the major partner of the striatin family members, which are scaffolding proteins involved in signaling and trafficking.
MOBKL3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-225 a.a.) and having a molecular mass of 28.1kDa. The MOBKL3 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PREI3: May play a role in membrane trafficking, specifically in membrane budding reactions. Belongs to the MOB1/phocein family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Activator; Protein kinase, regulatory subunit; Membrane protein, peripheral Chromosomal Location of Human Ortholog: 2q33.1 Cellular Component: cytoplasm; Golgi apparatus Molecular Function:protein binding |
| NCBI Summary: | This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011] |
| UniProt Code: | Q9Y3A3 |
| NCBI GenInfo Identifier: | 56749365 |
| NCBI Gene ID: | 25843 |
| NCBI Accession: | Q9Y3A3.1 |
| UniProt Secondary Accession: | Q9Y3A3,Q53SE0, Q7Z4Y6, Q9H2P3, Q9H5J1, Q9Y4T8, B4DML0 |
| UniProt Related Accession: | Q9Y3A3 |
| Molecular Weight: | 23,513 Da |
| NCBI Full Name: | MOB-like protein phocein |
| NCBI Synonym Full Names: | MOB family member 4, phocein |
| NCBI Official Symbol: | MOB4 |
| NCBI Official Synonym Symbols: | 2C4D; MOB1; MOB3; PHOCN; PREI3; CGI-95; MOBKL3 |
| NCBI Protein Information: | MOB-like protein phocein |
| UniProt Protein Name: | MOB-like protein phocein |
| UniProt Synonym Protein Names: | 2C4D; Class II mMOB1; Mob1 homolog 3; Mob3; Mps one binder kinase activator-like 3; Preimplantation protein 3 |
| Protein Family: | MOB kinase activator |
| UniProt Gene Name: | MOB4 |
| UniProt Entry Name: | PHOCN_HUMAN |
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