Human METAP1 Recombinant Protein (RPES0959)

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SKU:
RPES0959
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human METAP1 Recombinant Protein

Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs.

Product Name:Human METAP1 Recombinant Protein (RPES0959)
Product Code:RPES0959
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1, METAP1,MAP1A,MetAP1A
Accession:P53582
Sequence:Met1-Phe386
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human METAP1 is produced by our E.coli expression system and the target gene encoding Met1-Phe386 is expressed.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:43.2 kDa
AP Mol Mass:38&45-50 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM Tris,500mM NaCl,10%glycerol,pH8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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